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Weekend Edition essayist Andy Borowitz has his own personal (and humorous) take on the potential social benefits from the Human Genome map.

Puzzle master Will Shortz quizzes one of our listeners, and has a challenge for everyone at home. (This week's winner is David Slesnick from Pittsburgh, Pennsylvania. He listens to Weekend Edition on member station WDUQ.)

Host Bob Edwards talks to reporter John McLean about the recovery efforts in Manila after a mountain of garbage collapsed on a shantytown killing at least 71 people. Approximately one-hundred people were injured and an unknown number still missing. The mountain of garbage was weakened by a typhoon that swept through the Philippines last week.

In the second installment of our series on national missile defense, NPR's Mike Shuster examines some of the technical problems scientists would have to overcome, in order to make a missile defense system operational and effective.

Host Bob Edwards talks to John Bogle a personal finance pioneer and founder of the Vanguard Group, about mutual funds. Bogle criticizes the management practices of mutual funds and provides advise for consumers who are interested in investing in these funds.

Host Bob Edwards talks to Hirsch Goodman of the Jerusalem Report about Prime Minister Ehud Barak's political problems at home, in trying to negotiate with the Palestinians. Any transfer of land from Israel to the Palestinians would require the approval of Israel's Knesset, and Barak is in a relatively weak position with regard to that parliamentary body.

Host Bob Edwards talks with commentator John Feinstein about tonight's Major League All Star Game in Atlanta. The festivities began last night at Turner Field, when Sammy Sosa defeated Ken Griffey Junior to win the Home Run Derby.

Commentator Matt Miller says, he has an idea that will save Television executives from airing boring programs and serve a societal purpose. If death penalty fans consider capital punishment to be a deterrent, he says, airing executions should persuade people not to kill one another.

NPR's Ina Jaffe reports that a fourth police officer has been charged with misconduct in the ongoing probe of corruption in the Los Angeles Police Department. New charges have also been filed against two of three officers already facing trial.

Host Bob Edwards talks with Matt Ridley, a science writer for the London Telegraph and the author of the book Genome, about what the implications are for knowing how to map the entire human genome.